Epithalon
Research Use Only · Not for Human Consumption
A synthetic tetrapeptide (Ala-Glu-Asp-Gly) derived from the pineal extract epithalamin, supplied in lyophilized form.
A synthetic tetrapeptide developed at the St. Petersburg Institute of Bioregulation and Gerontology
Chemistry
| CAS# | Formula | Molar Mass |
|---|---|---|
| CAS Number: 307297-39-8 | Molecular Formula: C14H22N4O9 | Molar Mass: 390.35 g/mol |
What is Epithalon?
Epithalon is a synthetic tetrapeptide with the sequence Ala-Glu-Asp-Gly, originally derived from epithalamin, a pineal gland extract. It has been examined in preclinical and in vitro research investigating telomerase enzyme activity, chromosomal telomere dynamics, and gene-expression patterns in cultured cell lines.
Epithalon was developed in the former Soviet Union during the 1980s by Professor Vladimir Khavinson, whose laboratory was investigating the biochemistry of the pineal gland. Khavinson's group was characterizing how pineal-derived peptide fractions changed across different research models.
From pineal gland extracts, Khavinson's team isolated a peptide fraction named epithalamin. To produce a defined, reproducible research compound, the group synthesized a simpler four-amino-acid sequence (Ala-Glu-Asp-Gly) and designated it Epithalon.
The peptide has since been examined in preclinical and in vitro publications exploring telomerase enzyme activity and chromosomal telomere measurements. This product is intended for research use only.
How should Epithalon be stored?
Peptide Foundry research peptides are supplied lyophilized (freeze-dried). Keep sealed vials cool, dry, and protected from light until reconstitution.
After reconstitution, refrigerate prepared solutions and use sterile technique. For general laboratory diluent and handling notes, see lyophilized peptide reconstitution.
Certificate of Analysis
All Epithalon batches are independently tested by a third-party laboratory for purity and identity verification via HPLC with UV detection coupled with Mass Spectrometry.
HPLC Purity
99.29%
Product
Epithalon — 50mg
Lot Number
EPI50312
Appearance
White Lyophilized Powder
Measured Net Content
55.94 mg
Test Method
HPLC-UV / Mass Spectrometry
Report Date
03/15/2026
COA Number
2603130183
Laboratory
Freedom Diagnostics
No Certificate of Analysis is available for the selected size yet. Contact support for batch-specific documentation.
COA documents are updated with each new batch. Contact support for batch-specific documentation.
Further reading
References
- Khavinson VKh, et al. Epitalon peptide induces telomerase activity and telomere elongation in human somatic cells. Bulletin of Experimental Biology and Medicine. 2003.
- Khavinson VKh, et al. Effect of epithalon on the lifespan increase in Drosophila melanogaster. Mechanisms of Ageing and Development. 2000.
